Mutations in a protein known to cause Parkinson’s Disease derange transportation in and out of brain cells, reports a team of UConn Health researchers in the 27 July issue of Science Signaling. The toxic traffic jams that result eventually lead to certain brain cell death and the characteristic symptoms of Parkinson’s. “We figured out how […]
WEHI researchers have documented the diversity of cells in the human breast, explaining the relationship between healthy breast cells and breast cancer cells. The research, which relied on expertise spanning from breast cancer biology through to bioinformatics, measured gene expression in single cells taken from healthy women and cancerous breast tissue, including tissue carrying a […]
The impact on lung cells of Heat not Burn products—a hybrid between traditional cigarettes and electronic vaping devices—may be no less harmful than that of conventional cigarettes, suggest the findings of a small comparative study, published online in the journal Thorax. Heat not burn products contain nicotine and tobacco, but have been marketed by the […]
Scientists at Sanford Burnham Prebys Medical Discovery Institute demonstrated for the first time that blocking ‘cell drinking,’ or macropinocytosis, in the thick tissue surrounding a pancreatic tumor slowed tumor growth—providing more evidence that macropinocytosis is a driver of pancreatic cancer growth and is an important therapeutic target. The study was published in Cancer Discovery, a […]
Researchers from Children’s Hospital of Philadelphia (CHOP) have determined what happens at a cellular level as the lung alveolus forms and allows newborns to breathe air. Understanding this process gives researchers a better sense of how to develop therapies and potentially regenerate this critical tissue in the event of injury. The findings were published online […]
