Study suggests common drug could be used to prevent certain skin cancers

New data published by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) suggests that an oral drug currently used in the clinical setting to treat neuromuscular diseases could also help prevent a common form of skin cancer caused by damage from ultraviolet-B (UVB) […]

Healthy living helps ward off deadly prostate cancers in men at high risk

A nutritious diet, regular exercise and other components of a healthy lifestyle may reduce the odds of lethal prostate cancer in men with a high genetic risk for it, researchers report. “The excess genetic risk of lethal prostate cancer could be offset by adhering to a healthy lifestyle,” concluded co-lead author Anna Plym. She’s a […]

Treating patients with advanced biliary tract cancers: Changing tactics

Medical research very rarely has a single end point. There is often no final answer, or silver bullet, the science just continues to evolve, and with it, there will always be more to do, understand and investigate. But sometimes it reaches a tipping point, where the knowledge that’s been built up actually alters medical practice. […]

Heart-healthy lifestyles linked to lower risk of future cancers

In addition to lowering risk of heart disease, maintaining a heart-healthy lifestyle may pay off in lower risk for developing cancer, researchers from Massachusetts General Hospital (MGH) and other centers in the United States and the Netherlands have found. Looking at the potential link between cardiovascular disease (CVD) and cancer among participants in two large […]

Research team profiles histone mutational landscape of human cancers

Researchers in the Muir Lab at Princeton University’s Department of Chemistry have completed the first comprehensive analysis of cancer-associated histone mutations in the human genome, featuring both biochemical and cellular characterizations of these substrates. Their study reports that histone mutations that perturb nucleosome remodeling may contribute to the development or progression of a wide range […]

Proton therapy induces biologic response to attack treatment-resistant cancers

Mayo Clinic researchers have developed a novel proton therapy technique to more specifically target cancer cells that resist other forms of treatment. The technique is called LEAP, an acronym for “biologically enhanced particle therapy.” The findings are published today in Cancer Research, the journal of the American Association for Cancer Research. “The human body receives […]

Drug is promising against pancreatic and breast cancers

ProAgio, a drug developed by Georgia State University biology professor Zhi-Ren Liu and his team, is effective at treating pancreatic cancer and prolonging survival in mice, according to a study published in the journal Cellular and Molecular Gastroenterology and Hepatology. A second study, published in the Journal of Experimental Medicine, shows the drug is also […]

Blood test picks out cancers likely to benefit from targeted drugs

A simple and inexpensive blood test could pick out patients with stomach or oesophageal cancer who are likely to benefit from targeted treatment, a new study shows. The test, known as a liquid biopsy, detects cancer DNA in the bloodstream to reveal if stomach and oesophageal cancers are being driven by the presence of too […]

Cancer’s dangerous renovations to our chromosomes revealed

Cancer remodels the architecture of our chromosomes so the disease can take hold and spread, University of Virginia researchers have revealed. This remodeling is important because the arrangement of the components in our chromosomes actually affects the workings of our genes. With these renovations, cancer begins making a comfortable home for itself inside our cells. […]