A blood test already available to GPs in the UK is more predictive of ovarian cancer than previously thought and could also help pick up other forms of cancer, according to new research published in PLOS Medicine today (Wednesday) and funded by Cancer Research UK and NIHR. This study involving the University of Exeter was […]
Colon Cancer Screening Should Start at Age 45: Task Force
TUESDAY, Oct. 27, 2020 — Average folks should start being screened at age 45 to prevent colon cancer, five years earlier than is now recommended, the nation’s top preventive medicine panel says. The U.S. Preventive Services Task Force currently recommends that people aged 50 to 75 be regularly screened for colon cancer, one of a […]
Genome archeologists discover path to activate immune response against cancer
Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an infection. The work builds on Princess Margaret Senior Scientist Dr. De Carvalho’s previous ground-breaking discovery known as viral mimicry— the ability to cause cancer cells to behave as though they have been infected, thereby […]
Why It’s Important to Get Your Breast Cancer Screening, Even in a Pandemic
The American Association of Cancer Research published two studies in July that confirmed disruptions in regular breast cancer screening tests, including mammograms, ultrasounds, and MRIs. Some providers didn’t have enough resources to provide screenings amid the pandemic. Additionally, some people may have been afraid to get screenings at a hospital. Experts say it’s important to […]
Nudges combined with machine learning triples advanced care conversations among patients with cancer
An electronic nudge to clinicians—triggered by an algorithm that used machine learning methods to flag patients with cancer who would most benefit from a conversation around end-of-life goals—tripled the rate of those discussions, according to a new prospective, randomized study of nearly 15,000 patients from Penn Medicine and published today in JAMA Oncology. Early and […]
Genomic study of 6000 NCI-MATCH cancer patients leads to new clinical trial benchmarks
Five years ago, the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) and National Cancer Institute (NCI), part of the National Institutes of Health, jointly launched a very different kind of cancer study. NCI-Molecular Analysis for Therapy Choice (NCI-MATCH or EAY131), the largest precision medicine cancer trial to date, sought to match genetic abnormalities driving patients’ tumors with […]
Halting cancer by halting DNA repair
PARP inhibitors are rapidly transforming the treatment of ovarian, breast, prostate and other types of cancer. To develop these drugs, researchers supported by Cancer Research UK had to decipher how blocking DNA repair could expose a weak point in the biology of cancer cells. In the early 1990s, Steve Jackson seemed to have his career […]
Circular RNA molecule not found in cancer cells after all
A new research result from Aarhus University shows that a so-called circular RNA molecule, which has been designated as carcinogenic, is actually not found in cancer cells. The results have just been published in Nature Communications. In a major surprise, researchers from Aarhus University have discovered that an otherwise extensively studied carcinogenic RNA molecule is […]
Sterling K. Brown Stresses Importance of Mental and Emotional Support amid COVID-19 Pandemic
The year 2020 has been unlike any other, and Sterling K. Brown is doing his best to stay healthy — mentally, emotionally and physically — amid the ongoing coronavirus pandemic and the racial unrest in the country. "My family is doing well, we are figuring it out one day at a time. I don't think […]
Cancer centers to address pandemic’s impact on cancer prevention, treatment
A consortium of 17 U.S. cancer centers – including Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine – have come together to better understand the consequences of the COVID-19 pandemic in delaying cancer detection, care and prevention. The cancer centers are working together with the National Cancer Institute on the impact […]