Blood test predicts ovarian cancer better than previously thought

A blood test already available to GPs in the UK is more predictive of ovarian cancer than previously thought and could also help pick up other forms of cancer, according to new research published in PLOS Medicine today (Wednesday) and funded by Cancer Research UK and NIHR. This study involving the University of Exeter was […]

Colon Cancer Screening Should Start at Age 45: Task Force

TUESDAY, Oct. 27, 2020 — Average folks should start being screened at age 45 to prevent colon cancer, five years earlier than is now recommended, the nation’s top preventive medicine panel says. The U.S. Preventive Services Task Force currently recommends that people aged 50 to 75 be regularly screened for colon cancer, one of a […]

Genome archeologists discover path to activate immune response against cancer

Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an infection. The work builds on Princess Margaret Senior Scientist Dr. De Carvalho’s previous ground-breaking discovery known as viral mimicry— the ability to cause cancer cells to behave as though they have been infected, thereby […]

Why It’s Important to Get Your Breast Cancer Screening, Even in a Pandemic

The American Association of Cancer Research published two studies in July that confirmed disruptions in regular breast cancer screening tests, including mammograms, ultrasounds, and MRIs. Some providers didn’t have enough resources to provide screenings amid the pandemic. Additionally, some people may have been afraid to get screenings at a hospital. Experts say it’s important to […]

Genomic study of 6000 NCI-MATCH cancer patients leads to new clinical trial benchmarks

Five years ago, the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) and National Cancer Institute (NCI), part of the National Institutes of Health, jointly launched a very different kind of cancer study. NCI-Molecular Analysis for Therapy Choice (NCI-MATCH or EAY131), the largest precision medicine cancer trial to date, sought to match genetic abnormalities driving patients’ tumors with […]

Halting cancer by halting DNA repair

PARP inhibitors are rapidly transforming the treatment of ovarian, breast, prostate and other types of cancer. To develop these drugs, researchers supported by Cancer Research UK had to decipher how blocking DNA repair could expose a weak point in the biology of cancer cells. In the early 1990s, Steve Jackson seemed to have his career […]

Circular RNA molecule not found in cancer cells after all

A new research result from Aarhus University shows that a so-called circular RNA molecule, which has been designated as carcinogenic, is actually not found in cancer cells. The results have just been published in Nature Communications. In a major surprise, researchers from Aarhus University have discovered that an otherwise extensively studied carcinogenic RNA molecule is […]

Cancer centers to address pandemic’s impact on cancer prevention, treatment

A consortium of 17 U.S. cancer centers – including Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine – have come together to better understand the consequences of the COVID-19 pandemic in delaying cancer detection, care and prevention. The cancer centers are working together with the National Cancer Institute on the impact […]