A group of researchers from the United States discovered that the spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can induce the formation of highly inflammatory blood clots amenable to neutralization by a fibrin-targeting monoclonal antibody – opening the door for a completely new strategy to reduce thrombotic inflammation in coronavirus disease […]
Novel sensor could diagnose a heart attack in less than 30 minutes
Researchers from the University of Notre Dame and the University of Florida have developed a sensor that could diagnose a heart attack in less than 30 minutes, according to a study published in Lab on a Chip. Currently, it takes health care professionals hours to diagnose a heart attack. Initial results from an echocardiogram can […]
Blood marker could help ID those at risk of debilitating peripheral artery disease
To track cardiovascular health, doctors measure blood pressure, cholesterol levels and blood sugar, among a number of other cardiovascular disease risk factors. Such measures can help predict whether a person is at risk of heart attack or stroke. But there is no blood test that can accurately assess the degree to which a person’s arteries […]
Scientists offers new hope for future treatment of sepsis
Sepsis, the body's life-threatening response to infection affecting about 1.7 million adults in the United States each year, can lead to multisystem organ failure with a high mortality rate. No targeted therapeutics against this condition have been developed in the last decades. Now, however, a team led by biomedical scientists at the University of California, […]
Researchers examine the persistent effects of COVID-19 on vascular function of young adults
In a first-of-its-kind study, researchers have examined the persistent effects of SARS-CoV-2 infection on the vascular function of otherwise healthy young adults. The research, published in the American Journal of Physiology-Heart and Circulatory Physiology, was chosen as an APSselect article for September. “It is intriguing that those with persistent [COVID-19] symptoms exhibited peripheral vascular dysfunction, […]
Distinct changes found in cancer and non-cancer immune cells in Waldenstrom macroglobulinemia
A new study by researchers at Winship Cancer Institute of Emory University finds that cancer-associated mutations originate in blood progenitor cells, leading to distinct changes in both cancer and non-cancer immune cells in Waldenstrom macroglobulinemia (WM), a type of non-Hodgkin lymphoma and its precursor IgM monoclonal gammopathy of undetermined significance (MGUS). The study by Madhav. […]
Researchers show how to personalize treatments for patients with COPD
Patients with COPD are treated with drugs to improve the breathing ability in combination with inhaled corticosteroids to reduce the risk of acute worsening of the lung conditions. But the balance between reduced exacerbations and increased adverse effects of the drugs depends on the dose and on patient characteristics. Researchers from the University of Zurich […]
Antihypertensives may improve survival for patients with colorectal cancer
Common blood-pressure drugs may improve survival for patients with colorectal cancer, a new study suggests. After reviewing outcomes of almost 14,000 patients with colorectal cancer, researchers determined that ACE inhibitors, beta-blockers and thiazide diuretics were all associated with decreased mortality. They also found that patients who took their blood-pressure drugs consistently were less likely to […]
Brain memory signals may influence blood sugar levels, rat study finds
A set of brain signals known to help memories form may also influence blood sugar levels, finds a new study in rats. Researchers at NYU Grossman School of Medicine discovered that a peculiar signaling pattern in the brain region called the hippocampus, linked by past studies to memory formation, also influences metabolism, the process by […]
E-cigarette use during pregnancy poses health risk for offspring all the way into adulthood
The use of e-cigarettes (vaping) during pregnancy poses a significant health risk for the offspring, impairing blood vessel function even into adulthood, according to a new study by researchers at West Virginia University's (WVU) School of Medicine. Diminished blood vessel capacity increases the risk of stroke, heart attack and other cardiovascular problems. The research article […]