A team of researchers in the Center for Microbial Pathogenesis in the Abigail Wexner Research Institute at Nationwide Children’s Hospital recently characterized the anti-biofilm properties of HMGB1, a protein innate to eukaryotes and the immune systems of vertebrates, engineered modified molecules of the protein, and tested a therapeutic cocktail consisting of those molecules and antibodies […]
Artificial intelligence, or “supervised machine learning,” could help identify which well-appearing infants with fever, who are 60 days old or younger, are at low risk for a serious bacterial infection, according to a study published in Pediatrics. Accurate risk determination could reduce unnecessary lumbar puncture, antibiotics and hospitalizations for these infants, as well as decreasing […]
