Determining a child’s best daily balance of sleep, activity and relaxation can be a challenge, but if you’re hoping to improve their academic results, then it’s time to cut back on chores and chill time, according to new research from the University of South Australia. Exploring associations between 24-hour daily activities (sleep, sedentary time, light […]
Genetics and the COVID-19 pandemic
With the COVID-19 pandemic still raging worldwide, members of the American Society of Human Genetics (ASHG) are working to understand how the virus spreads and infects people, why there is so much variability in susceptibility and severity, and where to look for potential therapeutics. Researchers presented the results of several studies relevant to the current […]
Masks and Covid-19: In the US, a patchwork of policies persist
As the United States’ COVID-19 infection rate hits an all-time high, calls are growing for a nationwide mask mandate to replace the current patchwork of state regulations. One person who’s yet to be convinced, however, is President Donald Trump, who has consistently stressed treatments and future vaccines as the means to end the pandemic. Trump […]
GeneTx and Ultragenyx Announce Positive Interim Phase 1/2 Data on Investigational GTX-102 Demonstrating Improvement in Patients with Angelman Syndrome
SARASOTA, Fla. and NOVATO, Calif., Oct. 26, 2020 (GLOBE NEWSWIRE) — GeneTx Biotherapeutics LLC and Ultragenyx Pharmaceutical Inc. (NASDAQ: RARE), companies partnered in the development of intrathecally administered GTX-102, an investigational treatment for Angelman syndrome, today announced positive interim data from the Phase 1/2 study of GTX-102. Preliminary results from the first five patients treated […]
Research team identifies differences between benign and pathogenic gene variants
An international team of researchers led by Cleveland Clinic’s Lerner Research Institute has performed for the first time a wide-scale characterization of missense variants from 1,330 disease-associated genes. Published in Proceedings of the National Academy of Sciences, the study identifies features associated with pathogenic and benign variants that reveal the effects of the mutations at […]
I'm HIV positive and I don't just survive – I thrive
I’m proud to be HIV positive. I was diagnosed with HIV this time last year, at age 25. At first, my diagnosis was almost too hard to handle. I wrote suicide notes and planned my funeral via my notes app, fuelled by my belief that I wasn’t strong enough to cope with HIV, that I […]
Q&A: How to make and distribute a vaccine
A number of vaccines to combat the SARS-CoV-2 virus and the disease it causes, COVID-19, are currently undergoing various testing regimens. NC State’s Biomanufacturing Training and Education Center (BTEC) helps train the next generation of pharmaceutical workers. The Abstract spoke with BTEC’s Dr. Jennifer Pancorbo, director of industry programs and research and an expert on […]
New tool predicts risks of hospital admission and death from COVID-19
A new risk tool, developed by UK researchers to predict a person’s risk of being admitted to hospital and dying from COVID-19 has been published by The BMJ today. With cases increasing in the UK and elsewhere, and winter approaching, there is an urgent need for reliable models that predict the likely course of COVID-19, […]
What Is ‘Herd Immunity’ and Can It Stop COVID-19?
A concept bandied about early in the coronavirus pandemic, something called "herd immunity," has surfaced again. President Trump referenced the idea during an ABC News town hall last month, insisting the virus would eventually go away as people develop "a herd mentality." (Okay, he misspoke, but we think we know what he meant.) Then, during […]
Kids are exercising less and sitting more during the pandemic
Patterns set during childhood can influence adult life profoundly, and exercise habits are no exception. With the U.S. seeing a 20-year trend of increased risk of being overweight or obese among children, there’s reason for concern about both short- and long-term effects on health at a population level. Recent USC findings—from one of the first […]