Large genomic analysis highlights COVID-19 risk factors

In March of 2020, thousands of scientists around the world united to answer a pressing and complex question: what genetic factors influence why some COVID-19 patients develop severe, life-threatening disease requiring hospitalization, while others escape with mild symptoms or none at all? A comprehensive summary of their findings to date, published in Nature, reveals 13 […]

Updated analysis of US COVID-19 deaths shows drops, disparities in average lifespans

An updated analysis of American COVID-19 deaths throughout 2020 reveals an even bigger drop in average life expectancy as well as still-substantial disparities by race and ethnicity. Lead author Theresa Andrasfay, a postdoctoral scholar at the USC Leonard Davis School of Gerontology, and coauthor Noreen Goldman of Princeton University first examined the pandemic’s effect on […]

New method of gene analysis prevents early death in familial hypercholesterolemia

Researchers at Karolinska Institutet have investigated how a newly developed algorithm in connection with gene analysis can be used to improve the possibilities of preventing premature vascular disease and death in individuals with the hereditary lipid disorder, familial hypercholesterolemia. The findings, published in the Journal of Internal Medicine, show how the method can lead to […]

New single-cell analysis tool links immune cells to kidney cancer recurrence

The immune nature of kidney cancer stands out when compared to other cancers: More immune cells infiltrate kidney cancers than most other solid tumors, and kidney cancer is one of the most responsive malignancies to today’s immunotherapy regimens. But despite treatment, many patients with clear cell renal carcinoma—the most common type of kidney cancer—eventually relapse […]

Deprivation is ‘driving’ COVID-19 ethnic disparities, claims new analysis

Deprivation among society at large is ‘driving’ COVID-19 disparities among minority ethnic groups—predominantly South Asian and Black African or Caribbean populations—and could be considered the main cause of disproportionate infection rates, hospitalisation and deaths experienced by these populations, according to new analysis from the University of Leicester. The study, supported by the National Institute for […]

In mutant variants, has the coronavirus shown its best tricks?

LONDON/CHICAGO (Reuters) – The rapid rise in different parts of the world of deadly, more infectious coronavirus variants that share new mutations is leading scientists to ask a critical question – has the SARS-CoV-2 virus shown its best cards?FILE PHOTO: National Institutes of Health Director Francis S. Collins holds a model of SARS-CoV-2, the novel […]

Screening system for lung sound analysis

A multi-channel recording device developed at TU Graz for pathological lung sounds and associated automatic lung sound analysis could support existing screening methods for early detection of, for example, COVID-19 infections. This now requires clinical data and interdisciplinary collaboration. They whistle, hiss and crackle. Our bodies constantly make sounds that (fortunately) are not always audible […]