Cholesterol drives Alzheimer’s plaque formation, study finds

Cholesterol manufactured in the brain appears to play a key role in the development of Alzheimer’s disease, new research indicates. Scientists from the University of Virginia School of Medicine and their collaborators found that cholesterol produced by cells called astrocytes is required for controlling the production of amyloid beta, a sticky protein that builds up […]

Brain cells in Alzheimers patients consume resources essential to neurotransmission

Alzheimer’s disease (AD), the most common type of dementia, causes the death of neurons and leads to shrinking of the brain. Patients with AD will eventually experience gradual deterioration in memory, thinking, behavior and the ability to perform everyday activities. Yet, scientists do not fully understand what causes this disease. A recent study conducted by […]

Poor sleep impacts risk of long-term cognitive decline in Hispanic/Latino adults

Poor sleep impacts the risk of long-term cognitive decline in Hispanic/Latino middle aged and older adults differently than it does in non-Hispanic adults, according to research led by University of Miami Miller School of Medicine neurology faculty and the largest long-term study of U.S. Hispanic/Latinos to date. During seven years of follow-up, Hispanics/Latinos were more […]

Study projects significant savings from potential Alzheimer’s disease treatment

Alzheimer’s disease treatments that slow progression of the disease could significantly reduce the financial burden to U.S. state budgets, according to a new USC study. The study outlines how states—which have been hit particularly hard by the COVID-19 pandemic—would see relief: Medicare would cover the costs of treating the disease, while Medicaid expenditures would be […]

Diabetes type 2: The ‘irreversible’ signs of high blood sugar levels

Diabetes type 2: Dr Zoe Williams discusses high blood sugar risks When you subscribe we will use the information you provide to send you these newsletters.Sometimes they’ll include recommendations for other related newsletters or services we offer.Our Privacy Notice explains more about how we use your data, and your rights.You can unsubscribe at any time. […]

Lilly Alzheimer's drug shows benefit on cognition, function in mid-stage trial

(Reuters) – Eli Lilly and Co on Saturday said its experimental Alzheimer’s drug slowed the rate of decline in a measure of cognition and function by 32% compared with a placebo in a mid-stage trial of patients at an early stage of the mind wasting disease.FILE PHOTO: An Eli Lilly and Company pharmaceutical manufacturing plant […]

Study offers an explanation for why the APOE4 gene enhances Alzheimer’s risk

One of the most significant genetic risk factors for developing Alzheimer’s disease is a gene called APOE4, which is carried by almost half of all Alzheimer’s patients. A new study from MIT shows that this gene has widespread effects on brain cells’ ability to metabolize lipids and respond to stress. In studies of human brain […]

Covid jab may help fight cancer, chronic pain… and even Alzheimer's

The coronavirus jab’s most tantalising side effects? It may help fight cancer, chronic pain… and even Alzheimer’s Scientists have documented the unexpected benefits of vaccines for decades Some experts suggest vaccines can ‘train’ the immune system, strengthening it Others say increased stress hormones affect cells’ ability to target infections Joan Wakefield has barely been able to walk […]

First-in-human clinical trial to assess gene therapy for Alzheimer’s disease

Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer’s disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia. The […]

COVID vaccine advised for Alzheimer’s patients and their caregivers

All Alzheimer’s disease patients and their family caregivers should be vaccinated against COVID-19, the Alzheimer’s Foundation of America says. “Getting vaccinated is one of the most important steps families affected by Alzheimer’s disease can take to protect themselves and their loved ones,” said Dr. J. Wesson Ashford, chair of the foundation’s medical, scientific and memory […]