How protein PD-1 controls lymphoma cell metabolism, promotes cancer growth

Northwestern Medicine investigators have discovered how the protein PD-1 controls essential metabolic processes in tumor cells to promote cancer growth in T-cell non-Hodgkin lymphomas (T-NHLs), according to a study published in Nature Cancer. “We found that PD-1 controls the metabolism of these T-cell lymphoma cells, and these metabolic changes completely reprogram the epigenetics and transcriptional […]

Study suggests link between tear gas exposures and adverse reproductive health outcomes

83% of respondents reported at least one adverse reproductive health outcome, including uterine cramping, early menstrual bleeding, breast tenderness and delayed menstrual bleeding. Greater exposure to chemical agents was significantly associated with higher odds of an adverse reproductive health outcomes. Those with five days or more of exposure experienced 2.6 times more negative reproductive outcomes. […]

Brucella canis – you may have incurable dog disease for years before symptoms

There have been two laboratory-confirmed cases of Brucella canis (B. canis) in people within the UK. The first human case was detected following hospital admission; the woman affected had direct contact with abortion material from an imported dog. Dr Hana Patel, NHS GP and Medico-Legal Expert Witness, said: “Individuals at greatest risk of exposure to […]

New GP red tape prevent Brits 'getting care they need'

Are NHS waits set to get even longer? GPs told to ask before referring patients to hospital despite warning it will prevent Brits ‘getting care they need’ Called advice and guidance the model has a mixed reception from family medics READ MORE: GP practices bring back Covid masks for patients as cases surge GP and […]

Personalized cancer vaccine and adoptive T cell therapy benefits patients with advanced ovarian cancer: Study

A Ludwig Cancer Research study has shown that combining adoptive T cell therapy (ACT) with an innovative, personalized cancer vaccine under development at the Lausanne Branch of the Ludwig Institute for Cancer Research can benefit patients with late-stage, drug-resistant ovarian cancer. Researchers led by Ludwig Lausanne’s Sara Bobisse, Alexandre Harari, Lana Kandalaft and Director George […]