Breakthrough research has found that Group A Streptococcus (GAS) infections are more likely transmitted from asymptomatic throat carriage than skin-to-skin contact in communities with high rates of infection. This major discovery has far-reaching implications for public health approaches, vaccine development and future research as it challenges previous understanding of how the bacterium is spread. GAS […]
Characterizing the transition from skin to joint in psoriatic disease
The transition from psoriasis to psoriatic arthritis (PsA)—and the early diagnosis of PsA—is of considerable scientific and clinical interest. People typically have psoriatic skin disease for a decade or more before they begin to experience the joint involvement of PsA. Understanding more about the natural history and trajectory of this disease will help in the […]
Infantile botulism: Look for these signs and symptoms
Not being able to suck from a bottle or difficulty with feeding. Trouble swallowing. Pooling of breastmilk or formula in the mouth. Drooling of formula or breast milk from the mouth. Gurgling or choking sounds when trying to suck and swallow. Baby becoming weak and floppy. Source: Read Full Article
Genetic discovery leads to diagnoses of 9 people with rare form of muscular dystrophy
Nine people around the world who have been living with unexplained, muscular dystrophy-like symptoms may now have an answer for what is causing the progressive muscle weakness in their body’s mid-section, arms and legs. In a new discovery, a collaborative team of scientists led by researchers at Mayo Clinic’s Center for Individualized Medicine has pinpointed […]
Is the barefoot-boy summer trend bad for your feet? Experts explain
Riffing off 2019’s “hot girl summer” and 2022’s “Adam Sandler summer”, online magazine The Cut has declared 2023 the year of the “barefoot-boy summer”. American musician Mike Sabath and Euphoria actor Jacob Elordi were both papped walking barefooted earlier this year in Los Angeles. Meanwhile, Alexander Skarsgård’s Succession character (tech mogul Lukas Matsson) was also […]
Are we REALLY at a 'turning point in the fight against Alzheimer's'?
Are we REALLY at a ‘turning point in the fight against Alzheimer’s’? Breakthrough new drugs halt cruel disease’s decline… but experts warn crippling side effects (and cost) may outweigh any benefits Donanemab stopped mental decline for a year in around half of patients But questions are being asked whether the US drug is really the […]
Research shows diagnostic error as a leading cause of death and disability
Reviewers’ Notes Improving diagnosis in health care is a moral, professional and public health imperative, according to the U.S. National Academy of Medicine. However, little is known about the full scope of harms related to medical misdiagnosis — current estimates range widely. Using novel methods, a team from the Johns Hopkins Armstrong Institute Center for […]
American Heart Association calls for more research on e-cigarettes
Reviewers’ Notes Research increasingly reveals health risks of e-cigarette use, and more studies are needed about the long-term impact e-cigarettes may have on the heart and lungs, according to a new scientific statement from the American Heart Association published today in the Association's flagship journal Circulation. The new scientific statement, "Cardiopulmonary Impact of Electronic Cigarettes […]
Land Conservation Benefits Wealthy White Landowners
New land conservation projects tend to offer financial benefits to wealthy, White landowners who neighbor the region by boosting property values, according to research conducted by the University of Rhode Island and University of Illinois Urbana-Champaign. What to know: Of the $9.8 billion in property wealth generated by conservation from 2001 to 2009 nationwide, 89% […]
Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes
In a recent study posted to the preprint server Research Square* while under review for publication in Epigenetics & Chromatin, researchers develop and characterize a highly specific EpiEditing system using catalytically inactivated Cas9 (dCas9) to achieve allele-specific deoxyribonucleic acid (DNA) methylation (ASM). Study: Development of super-specific epigenome editing by targeted allele-specific DNA methylation. Image Credit: Natali _ […]