Researchers create an integrated pipeline for performing genetic screening studies

Today's genetic engineers have a plethora of resources at their disposal: an ever-increasing number of massive datasets available online, highly precise gene editing tools like CRISPR, and cheap gene sequencing methods. But the proliferation of new technologies has not come with a clear roadmap to help researchers figure out which genes to target, which tools […]

Drug withdrawal morphs brain communication networks in mice

Zeroing in on specific brain regions when studying drug and alcohol abuse simplifies research but may leave out important insights. In fact, the landscape of the entire brain reorganizes during withdrawal, potentially hindering communication between regions, according to new research in mice published in eNeuro. Kimbrough et al. administered psychostimulant drugs to mice (cocaine, methamphetamine, […]

Study finds increase in cannabis use by pregnant women during the pandemic

A Kaiser Permanente analysis of more than 100,000 pregnancies in Northern California finds a 25% increase in the rate of cannabis use early in pregnancy after the pandemic began in spring 2020. The analysis was reported in a research letter in the September 27 issue of JAMA. The study found that in the year before […]

Prevalence of primary sclerosing cholangitis in IBD examined

(HealthDay)—The global prevalence of primary sclerosing cholangitis (PSC) ranges from 0.96 percent in Crohn disease (CD) to 2.47 percent in ulcerative colitis (UC), according to a review published online Aug. 19 in Gastroenterology. Brigida Barberio, M.D., from the University of Padova in Italy, and colleagues conducted a systematic literature review and meta-analysis to assess the […]

Common pain reliever safe for use in children with inherited blood cell disorder

Red blood cells in the human body are continuously subjected to oxidative stress, in which highly reactive molecules damage cellular components. Blood cells have a mechanism in place to deal with this stress, an enzyme called glucose-6-phosphate dehydrogenase (G6PD). But in about 400 million people worldwide, G6PD is deficient, leaving blood cells vulnerable to oxidation […]

Mask mandates in schools curb infections, CDC studies show

(HealthDay)—Wearing masks in schools appears to sharply curtail the spread of COVID-19, despite the dominance of the highly contagious Delta variant, two new U.S. studies show. Published by the U.S. Centers for Disease Control and Prevention, the reports found there were fewer outbreaks in schools that required masks. In the first study, researchers focused on […]

Vin Diesel Just Teased a New ‘Riddick’ Sequel With a Shirtless Photo

Not content with having one hugely successful and long-running action movie franchise in the Fast & Furious series, Vin Diesel is keen to bring back one of his other famous characters: Riddick, the lethal antihero who he first portrayed in 2000’s Pitch Black, a full year before the first Fast movie. He’s already reprised that […]

COVID-19: Llama nanobodies may offer new treatment

Although vaccines are highly effective in preventing COVID-19, scientists still need to identify better treatments for the disease. Some scientists are investigating whether llama-derived antibodies might be a useful treatment approach. A recent study has shown that so-called nanobodies that scientists harvested from a llama reduced SARS-CoV-2 viral load in Syrian hamsters. In the race […]

These schools use weekly testing to keep kids in class — and covid out

On a recent Monday morning, a group of preschoolers filed into the gymnasium at Hillside School in the west Chicago suburbs. These 4- and 5-year-olds were the first of more than 200 students to get tested for the coronavirus that day — and every Monday — for the foreseeable future. This story is part of […]