Metabolic memory plays a key role in breast cancer relapse

Molecular targets for therapies that could prevent breast cancer recurrence have been identified by a group of German, Norwegian and British scientists who analyzed tumor cells that proved resistant to the original treatment. Recent advances in early detection and targeted therapy have led to a growing success in treating breast cancer upon first presentation. This […]

Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a ribonucleic acid (RNA) virus that causes the coronavirus disease 2019 (COVID-19). RNA viruses are prone to high rates of mutation. In fact, it has been reported that in SARS-CoV-2, 10−3 substitutions occur on each site of the virus every year. Study: Mutational hotspot in the SARS-CoV-2 […]

New York’s Largest HCP Fires 1400 Unvaccinated Employees

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Northwell Health, the largest hospital system in New York state, fired 1,400 employees on Monday for not complying with the state’s COVID-19 vaccine mandate. The employees represented less than 2% of Northwell’s 76,000 employees, who are now all fully vaccinated against […]

Potential new treatment for COVID-19 identified

Researchers have identified a potential new treatment that suppresses the replication of SARS-CoV-2, the coronavirus that causes COVID-19. In order to multiply, all viruses, including coronaviruses, infect cells and reprogram them to produce novel viruses. The research revealed that cells infected with SARS-CoV-2 can only produce novel coronaviruses when their metabolic pentose phosphate pathway is […]

Entrepreneur has food allergies. So he made a life-saving phone case

As a young adult, Javier Evelyn didn’t always carry his epinephrine autoinjector, which dispenses the medicine he needs if he has a food allergy reaction. It wasn’t cool to carry a clunky piece of equipment, he recalled. “I did not carry my device with me at all for most of college, so I was just […]

Anti-cancer drug derived from fungus shows promise in clinical trials

A new industry-academic partnership between the University of Oxford and biopharmaceutical company NuCana as found that chemotherapy drug NUC-7738, derived from a Himalayan fungus, has 40 times greater potency for killing cancer cells than its parent compound. Oxford University researchers have worked in collaboration with industry leaders NuCana to assess a novel chemotherapy drug derived […]