A novel investigational allogeneic stem cell-derived treatment resulted in near reversal of type 1 diabetes in a patient who had lived with the condition for about 40 years. The patient was the first in Vertex Pharmaceuticals’ phase 1/2 multicenter, single-arm, open-label clinical trial of the insulin-producing islet cell therapy VX-880 for patients with type 1 […]
Researchers at Washington University School of Medicine in St. Louis have received a five-year, $9.1 million grant from the National Institute on Aging of the National Institutes of Health (NIH) to study resilience in older adults before and during the COVID-19 pandemic. The grant also will fund research into the pandemic’s cognitive and emotional effects […]
The Psoriasis Area and Severity Index (PASI) clearance trajectory over the first few weeks of type B ultraviolet (UVB) phototherapy may predict psoriasis clearance, according to a study published in the November issue of the Journal of the European Academy of Dermatology and Venereology. Nicola Watson, from the Newcastle Hospitals NHS Foundation Trust in the […]
Trying to have a baby can feel like a secret odyssey, filled with private ups and downs (and concocting believable reasons you’re not having cocktails). If you don’t get the great news you’re pregnant right away, this time can be stressful and isolating. The truth is — even with a clear picture of what’s going […]
NEW YORK (Reuters Health) – In patients undergoing non-cardiac surgery under general anesthesia, intraoperative mean arterial pressure (MAP) of less than 55 mm Hg is associated with increased risk of postoperative delirium within 30 days of surgery, according to a new study. And the longer hypotension lasted, the greater the odds of delirium, Dr. Matthias […]
The number of adenomas per colonoscopy (APC) is inversely correlated with postcolonoscopy colorectal cancer (PCCRC), which supports use of APC as a new quality control measure, according to investigators. Data from 138 endoscopists showed that patients screened by physicians with higher APCs had significantly lower rates of PCCRC, and an APC of 0.6 offered more […]
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Nearly one in three gay and bisexual men who were diagnosed with HIV at UK sexual health clinics didn’t meet the criteria for “high risk” that would signal to a clinician that they would be good candidates for pre-exposure prophylaxis (PrEP). And that means that people who appear lower risk may still be good candidates […]
Data from the 28-week extension of the LIBERTY EoE TREET phase 3 clinical trial showed that the anti–interleukin-4/IL-13 antibody dupilumab led to long-term improvement in eosinophil count, histology, and patient-reported symptoms of eosinophilic esophagitis (EoE) out to 28 weeks. Dupilumab is Food and Drug Administration approved for the treatment of atopic dermatitis, asthma, and chronic […]
An assessment of deaths attributable to police violence in the United States concludes that half of all such killings are misclassified or misreported. The analysis finds that Black people are the most likely of all racial and ethnic groups to die as a result of police violence. The study authors conclude that militarized policing and […]
