The Use of Optical Filters in Flow Cytometry

Flow cytometry is a high-throughput method of cell analysis wherein live cells are passed in single file by a series of lasers and detectors. The degree of scattering experienced by the laser light can be used to infer a significant degree of information regarding the cell, such as size, density, morphology, and state of apoptosis, […]

Could Viagra Help Prevent Alzheimer’s?

The erectile dysfunction medication Viagra could potentially be used as a treatment for Alzheimer’s disease, according to a new study published in the journal Nature Aging. Patients who used the drug sildenafil, the generic name for Viagra, were 69% less likely to develop the disease than nonusers. “Sildenafil, which has been shown to significantly improve […]

Abrocitinib Efficacy Dose-Dependent, Similar Across AD Age Groups

Responses to abrocitinib treatment among patients with moderate to severe atopic dermatitis (AD) showed dose-dependent consistency across age groups and was comparable in patients aged 51 years and older, results from a post-hoc analysis of four trials showed. Abrocitinib (Cibinqo) is an oral, once-daily, Janus kinase 1 selective inhibitor that has shown good efficacy and […]

Does vaping really damage DNA and increase the risk of cancer?

Vapers experience DNA changes, according to a recent paper published in Nature, and the changes are similar to those seen in smokers—although much less pronounced. Crucially, this evidence was based on a few people by examining changes in their DNA at the time of the analysis, similar to creating a snapshot image, without considering any […]

Effect of mutations on SARS-CoV-2 E protein interactions with cell junctions

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein has a C-terminus with a PDZ binding motif (PBM) that targets PDZ (PSD-95/Dlg/ZO-1) domains. This motif is identical to the SARS-CoV PBM. In a recent study published on the bioRxiv* preprint server, ten human PDZ-containing proteins were identified, which showed significant interactions with the […]

COVID-19: WHO’s stance on convalescent plasma sparks controversy

The World Health Organization (WHO) does not recommend convalescent plasma as a treatment for COVID-19. The new decision comes from the analysis of findings from 16 studies. However, an expert takes exception to the WHO’s conclusion. The treatment targets specific variants of the SARS-CoV-2 virus. On December 6, 2021, the WHO revised its “living guideline,” […]

Gout diet: The £1.30 fruit juice to help avoid painful symptoms

BBC Breakfast: Charlie Stayt reveals in 2014 that he had gout We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Gout is famously caused […]