CAR-T Cell Therapy for Multiple Myeloma May Lead to Parkinson-Like Symptoms

NEW YORK (Reuters Health) – Researchers at Mount Sinai in New York have reported a previously unknown neurological side effect in a patient with multiple myeloma who received CAR-T cell therapy in a clinical trial. The 58-year-old patient developed a progressive movement disorder with features of parkinsonism roughly three months after finishing a course of […]

Microbiota May Predict Success on Low FODMAP Diet

Two distinct gut microbiota subtypes showed an enhanced clinical response to a low FODMAP diet in an analysis of 41 adults with irritable bowel syndrome and household controls. Irritable bowel syndrome (IBS) has a significant impact on quality of life, and some patients find relief on a low FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) […]

How to Stay Healthy When Everyone in Your House Is Sick

It is officially cold and flu season (and we’re seeing with Omicron another wave of coronavirus cases) — which means everyone around you is at risk of getting sick. Ugh. While you might be able to avoid coughing and sneezing at work by avoiding those who are infected, what happens when you’re the only healthy […]

CRISPR/Cas9 gene editing boosts effectiveness of ultrasound cancer therapy

Sonodynamic therapy uses ultrasound in combination with drugs to release harmful reactive oxygen species (ROS) at the site of a tumor. However, the treatment isn’t very effective because cancer cells can activate antioxidant defense systems to counteract it. Now, researchers reporting in ACS Central Science have breached these defenses with CRISPR/Cas9 gene editing, allowing sonodynamic […]

Gallic acid and stretching decrease osteoarthritis markers in cartilage cells

A healthy diet and a little exercise appear to be good for arthritis, even on the cellular level. A team led by Washington State University researchers used gallic acid, an antioxidant found in gallnuts, green tea and other plants, and applied a stretching mechanism to human cartilage cells taken from arthritic knees that mimics the […]

About 40 percent with confirmed COVID-19 are asymptomatic

(HealthDay)—The percentage of asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is 0.25 and 40.50 percent among individuals undergoing testing and those with confirmed COVID-19, respectively, according to a review published online Dec. 14 in JAMA Network Open. Qiuyue Ma, Ph.D., from Peking University in Beijing, and colleagues examined the percentage of asymptomatic infections […]

Video: Will current COVID-19 treatments and therapies work against omicron?

Researchers are aggressively studying the emergence of the omicron variant. One of the many questions they’re hoping to answer is how well current COVID-19 treatments and therapies will work against omicron. “If you look at the structure of omicron and compare it to the structure of previous strains, including delta, the site where there is […]