Positive Topline Results for siRNA in Raised Lipoprotein(a)

Topline results from the phase 1 APOLLO study of SLN360, a short interfering ribonucleic acid (siRNA) targeting lipoprotein(a), showed it significantly reduced Lp(a) in a dose-dependent manner from 46% to up to 98%. Reductions of up to 81% were maintained out to 150 days, according to a release from the developer of the drug, Silence Therapeutics. High […]

Philippines to re-open to vaccinated foreign tourists

The Philippines will re-open to fully vaccinated tourists from most countries on February 10 and lift quarantine requirements, officials said Friday, nearly two years after closing its borders to contain the coronavirus. Tourism operators across the archipelago nation famed for its beaches and dive spots have been devastated by a plunge in international visitors and […]

Vietnam Fires Deputy Health Minister Accused of Fake Meds Scam

HANOI (Reuters) – Vietnam on Wednesday fired a deputy health minister, months after he was accused of involvement in a fake medicine trading ring, the government said on Wednesday. Truong Quoc Cuong, 59, “committed serious violations and weakness while on duty between 2007 and 2016”, the government said in a statement. Cuong violated the regulations […]

New research may pave the way to better treatments for Crohns disease

A paper published this week in Immunity, a research journal highlighting discoveries in immunology, lays the groundwork to better understand and treat Crohn’s disease, a type of inflammatory bowel disease (IBD). Beneficial interactions among intestinal cell types limit the harmful effects of a dysregulated gut microbiota, which is comprised of trillions of bacteria, viruses, and […]

The Battle of Egos Behind the Life-Saving Discovery of Insulin

Editor’s Note: This is the first in a two-part series commemorating the 100 year anniversary of the first use of insulin in humans. The second part focuses on how insulin and the treatment of type 1 diabetes have changed over the past 100 years and what to expect in the next 100. Leonard Thompson’s father was so […]

Where mental health help is scarce, telehealth makes a big difference

When the nearest psychiatrist’s office is dozens or even hundreds of miles away, a virtual connection may be enough to help people living with serious mental health conditions get effective care through their local primary care clinic, a new study shows. The randomized study of just over 1,000 people with post-traumatic stress disorder, bipolar disorder […]

Surrogate Endpoints Acceptable in AML Trials, Says FDA

The US Food and Drug Administration (FDA) has been harshly critized for using surrogate endpoints in clinical trials in its approval of new drugs, and especially so in oncology, where critics have argued that the only truly meaningful endpoint is overall survival (OS). But the FDA is now fighting back and is arguing that in […]

The difference between foods containing cholesterol and foods causing high cholesterol

High cholesterol: Nutritionist reveals top prevention tips We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Does eating high cholesterol foods cause high cholesterol? […]

How does COVID-19 cause loss of smell?

Scientists are unsure why COVID-19 causes smell loss in so many people because the virus that causes the disease, SARS-CoV-2, cannot infect olfactory sensory neurons. A new study in hamsters suggests that the infection of neighboring cells may trigger a reorganization in the nuclei of these sensory neurons. This reorganization appears to disrupt the production […]

Nature vs. Steroids: A Detailed Decision-Making Guide

What are steroids? Synthetic anabolic steroids were developed in the 1930s and are primarily derivatives of testosterone. All steroids provide muscle growth, increased strength, and other desirable results. One of the biggest differences between steroid users and natural athletes is speed. By disrupting normal hormonal processes, anabolic steroids can have both positive and negative consequences. […]