New support for using time in target range (TTR) to assess the clinical impact of renal denervation and lifetime burden of disease in patients with uncontrolled hypertension comes from two analyses presented at EuroPCR 2022. Between 6- and 36-month follow-up in the Global SYMPLICITY Registry, the major adverse cardiovascular event (MACE) rate was 2.9% in […]
Gut bacteria can reduce the effectiveness of certain blood pressure drugs
A new study from The University of Toledo College of Medicine and Life Sciences has shown gut bacteria can reduce the effectiveness of certain blood pressure drugs. The research, published this month in the journal Hypertension, offers the first clues to what has been an elusive mystery -; why do some people not respond well […]
Comorbidities can increase plasma biomarker levels associated with Alzheimer’s disease
A simple blood test to diagnose Alzheimer’s disease, perhaps even years before symptoms appear, is an exciting possibility, but a new study shows that much more research is needed before these blood tests are routinely used in the clinical diagnostic setting. The study appears online in the current issue of Nature Medicine. Two hallmarks of […]
Treatment for myelodysplastic syndrome by hypomethylating agents may activate an oncogene
Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS), and increasingly in other diseases, but their mechanism of action is not clear. HMAs may affect many genes and could potentially activate an oncogene—a gene that contributes to the development of cancer—but this has not been clearly demonstrated to […]
Improving Cross-Cultural Communication Skills With Patients
INDIANAPOLIS ― With a focus on helping fellow practitioners improve their patient-care skills, members of the Diversity, Equity, and Inclusion (DEI) Commission of the American Academy of Physician Associates (AAPA) presented a wide-ranging session on cross-cultural communication at the group’s 2022 annual meeting. Robert Lee Wooten Commission chair Robert Lee Wooten, PA-C, noted that cross-cultural […]
Seven healthy habits to cut dementia risk
Steve Thompson recalls signs of his early-onset dementia We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info The seven factors identified by experts are: […]
Man who suffered child sex abuse now helps other survivors share their stories
Child sex abuse isn’t something we like to think about happening – but we can’t afford to turn a blind eye. Jeremy Indika, a 36-year-old living and working in Colchester, knows this only too well. From the age of eight he was sexually abused for two years by a trusted close friend of his family. […]
Why running is actually a great workout for your arms (if you use them properly)
Want to run a faster 5k? You’re going to have to strengthen more than just your legs. We speak to the experts on the role that arms play in running fast. To run, you need three things: strong glutes, a decent diet and a good dose of determination. Don’t fuel adequately and you won’t make […]
Variceal Embolization During TIPS Placement Does Not Reduce Rebleeding
New York (Reuters Health) – Variceal embolization during transjugular intrahepatic portosystemic shunt (TIPS) placement does not reduce patients’ risk of recurrent variceal bleeding, new data show. Dr. Yong Lv et al from the Xijing Hospital of Infectious Diseases, Xi’an, China and colleagues randomly assigned 134 adults with liver cirrhosis and gastro-esophageal bleeding to undergo either […]
Using ketamine to find an undiscovered pathway in depression
For the 280 million people suffering from depression globally, relief cannot come fast enough. Monoaminergic antidepressants, including selective serotonin reuptake inhibitors (SSRIs) take weeks to months to take effect and do not work for more than one in three patients. For patients diagnosed with treatment-resistant depression, or in immediate crisis, access to safe, effective, rapid-acting […]