Babies born to mothers who suffered COVID-19 disease during pregnancy seem to exhibit differences in neurodevelopmental outcomes at 6 weeks, according to a preliminary analysis presented in the 30th European Congress of Psychiatry. Project Leader Dr Rosa Ayesa Arriola said: "Not all babies born to mothers infected with COVID show neurodevelopmental differences, but our data […]
Drug combination shows promise against cancers death star protein
A drug combination targeting multiple mutant versions of cancer’s “death star” protein has shown promise in a small, early-phase clinical trial for some patients with advanced lung, ovarian and thyroid cancer. The two-drug combination was effective against advanced cancers with a range of mutations to the KRAS gene—dubbed the “death star” because its protein drives […]
Enhertu Benefit in HER2-Low Breast Cancer: ‘Practice Changing’
CHICAGO — Breast cancer patients with low levels of HER2 expression, previously considered untreatable with HER2-targeted therapies, benefited from the anti-HER2 antibody drug conjugate trastuzumab deruxtecan. The therapy doubled progression-free survival versus chemotherapy in patients with hormone receptor positive (HR+) and low levels of HER2. “Overall, these results establish HER2 low metastatic breast cancer as a targetable […]
Nursing shortfall 'will only be improved by above-inflation pay rise'
Union demands NHS nurses get an inflation-busting salary hike worth up to £4,000 to avoid mass exodus Nurses union said below-inflation pay rise would be ‘another pay cut’ for nurses Bosses say 12.8 per cent pay rise is needed for medics to improve staffing levels It comes UK Government are due to announce pay awards […]
The best exercises to pair if you want to build muscle while saving time
Supersets aren’t just another fitness buzzword. Here’s how to use the training style for building muscle and mixing up your workouts. Simply deciding what workout to do is the first hurdle for those who are trying to get back into the gym after an exercise break (or even just after the bank holiday weekend). Of […]
Is there really such a thing as a ‘gut feeling’?
Written by Lauren Geall As Stylist’s digital writer, Lauren Geall writes on topics including mental health, wellbeing and work. She’s also a big fan of houseplants and likes to dabble in film and TV from time-to-time. You can find her on Twitter at @laurenjanegeall. Our gut plays an important role in breaking down food and […]
Trial of peptide-centered SARS-CoV-2 T-cell activator in B-cell deficient individuals
A recent phase 1/2 study under review at the Nature Portfolio journal and posted to the Research Square* preprint server demonstrated that a peptide-centered severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) T-cell activator, CoVac-1, was efficient in B-cell deficient people. Study: Phase I/II trial of a peptide-based COVID-19 T-cell activator in patients with B-cell deficiency. Image […]
Dementia: Young mum mistook the brain condition for post-natal depression – signs
Frontotemporal dementia symptoms include 'changes in personality' We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Holly Braithwaite was 34 years old when she […]
‘Great Optimism’ Over Complete Responses in dMMR Rectal Cancer
Patients with locally advanced rectal cancer and tumors with deficient mismatch repair (dMMR) have shown a remarkable response to treatment with the programmed cell death-1 (PD-1) inhibitor dostarlimab (Jemperli). So far, the study has involved only 12 patients, but all of them have had a clinical complete response to treatment. They continue to show no […]
Vascular dementia symptoms: ‘Memory problems may not be an issue initially’ – signs
There are a number of early signs of vascular dementia according to Helen Green, Admiral Nurse at Dementia UK. She explained vascular dementia is the second most common form of dementia and it is caused by disruption of the blood supply to the brain preventing oxygen reaching the cells of the brain. She said memory […]