What is the association between natural killer cell dysfunction and COVID-19 disease severity?

In a recent review published in Cell Biochemistry and Function, researchers assessed the association between natural killer (NK) cell dysfunction and coronavirus disease 2019 (COVID-19) disease severity. Study: NK cell dysfunction is linked with disease severity in SARS-CoV-2 patients. Image Credit: Numstocker/Shutterstock Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections are characterized by symptoms including […]

Machine learning models help forecast immunotherapy response from gut microbiomes

A new research paper was published in Oncotarget on July 19, 2022, entitled, "Predicting cancer immunotherapy response from gut microbiomes using machine learning models." "In the last decade, the use of cancer immunotherapy targeting immune checkpoint inhibitors (ICIs) to boost T cell mediated cancer cell clearance has significantly improved cancer patient survival." Cancer immunotherapy has […]

‘Junk’ DNA could lead to cancer by stopping copying of DNA

Scientists have found that non-coding “junk” DNA, far from being harmless and inert, could potentially contribute to the development of cancer. Their study has shown how non-coding DNA can get in the way of the replication and repair of our genome, potentially allowing mutations to accumulate. It has been previously found that non-coding or repetitive […]

Study finds heart conditions extremely rare after COVID-19 vaccination

A Canadian study shows that myocarditis and pericarditis after COVID-19 mRNA vaccinations are extremely rare. This research also suggests that spacing out second doses to 30 days and offering Pfizer vaccines over Moderna might lower the risk of developing these conditions in men ages 12-29. Experts stress that developing COVID-19 poses a greater risk of […]

Think of Pediatric Morphea as a Systemic, Chronic Disease

INDIANAPOLIS – In the opinion of Elena Pope, MD, MSc, it’s time to think of morphea in children as a systemic, chronic condition with associated extracutaneous manifestations and the potential for relapse. “There is no correlation between the extent and activity of skin lesions and the presence, severity, and activity of extracutaneous manifestations,” Pope, professor […]

COVID-19 patients more likely to develop cardiovascular diseases and diabetes soon after infection

Patients who contract COVID-19 face a higher risk of developing cardiovascular diseases and diabetes, particularly in the three months following infection, according to a new study by Emma Rezel-Potts, Martin Gulliford, and colleagues of King’s College London, United Kingdom, publishing July 19th in the open access journal PLOS Medicine. Scientists are increasingly recognizing COVID-19 as […]