Researchers create specific cancer organoid system to study bacterial effects on immunotherapy

Wake Forest Institute for Regenerative Medicine (WFIRM) researchers are using a tumor organoid system to examine the effects of metabolites secreted by bacteria on a specialized immunotherapy—immune checkpoint blockage, a promising cancer treatment development—to determine why some patients don’t respond or develop a resistance to the treatment over time. According to Cancer.gov, immune checkpoints are […]

Progress toward a stem cell–based therapy for blindness

What if, in people with blinding retinal disorders, one could simply introduce into the retina healthy photoreceptor cells derived in a dish from stem cells, and restore sight? It’s a tantalizingly straightforward strategy to curing blindness, yet the approach has been met with a number of scientific roadblocks, including introduced cells dying rapidly or failing […]

Doctors, Individualize Care for Patients Without Heart Risks

Clinicians should decide on a case-by-case basis whether adults without risk factors for cardiovascular disease (CVD) should receive behavioral health counseling to promote a healthier diet and more exercise, according to new guidance from the US Preventive Services Task Force (USPSTF). The recommendations, published Tuesday in the Journal of the American Medical Association, are based […]

New Blood Test Could Reshape Early CRC Screening

A simple blood test that looks for a combination of specific RNA snippets may become a novel way to screen for early-onset colorectal cancer, suggests a new study published online in Gastroenterology. Researchers identified four microRNAs that together comprise a signature biomarker that can be used to detect and diagnose the presence of colorectal cancer […]

Promising eco-friendly plug to treat nosebleeds

Nosebleeds, also known as epistaxis, are one of the most frequent otolaryngologic (ENT) emergencies worldwide. It is estimated that 60% of the world’s population will experience an episode of epistaxis at least once in their lifetime, although only 6–10% of them will seek medical attention. There are several methods for treating epistaxis and one of […]

Are 'psychobiotics' the way to better mental health via the gut?

The gut-brain axis is well documented, but now psychobiotics are being investigated for their mental health-supportin gproperties.  A few years ago, you might only have glanced at the gut health aisle of your local health and wellbeing emporium if you had stomach issues. Now, that aisle is packed full of pre-, pro- and postbiotic supplements […]

AI-based tools have failed to reach the full diagnostic potential in COVID-19, study finds

Published by the Journal of Radiology: Artificial Intelligence, a prospective observational study across 12 hospital systems from the University of Minnesota Medical School evaluated the real-time performance of an interpretable artificial intelligence (AI) model to detect COVID-19 from chest X-rays. Participants with COVID-19 had a significantly higher COVID-19 diagnostic score than participants who did not […]