Dupilumab Improves Eosinophilic Esophagitis Up to 24 Weeks

Dupilumab appears to improve clinical, symptomatic, histologic, and endoscopic aspects of eosinophilic esophagitis (EoE) up to 24 weeks, according to findings presented at the annual meeting of the American College of Gastroenterology. The drug was also well tolerated, demonstrating consistency with the known dupilumab safety profile, said Evan S. Dellon, MD, a gastroenterologist at the University of […]

AI trained to detect hard to spot cancerous lesions in colon

An artificial intelligence (AI) tool, developed by scientists at UCL, UCLH and UCL-spinout Odin Vision, has been further refined to identify hard to spot “flat” polyps, that—when left untreated—can become highly aggressive and are a major cause of colorectal (bowel) cancer. For the study, published last year in Digestive Endoscopy, the research team trained the […]

What is the impact of SARS-CoV-2 on HIV-1 infectivity?

In a recent study posted to Research Square* preprint server, researchers assessed the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-CoV envelope (E) proteins on human immunodeficiency virus type 1 (HIV-1) infectivity. Study: The Envelope Proteins from SARS-CoV-2 and SARS-CoV Potently Reduce the Infectivity of Human Immunodeficiency Virus type 1 (HIV-1). Image […]

NHS nurses balloted for strike action over pay

We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info For the first time in its 106-year history, members of the Royal College of Nursing […]

Does COVID-19 spread in schools?

Shiranee Sriskandan, professor of infectious disease within the Department of Infectious Disease at Imperial College London, explains how a study of COVID-19 in London schools provides insights for this winter and future infectious disease outbreaks. In 2020, when COVID-19 first emerged, concerns of the risks to the most vulnerable in society, including children, were high. […]

ALL-HEART: No Benefit of Allopurinol in Ischemic Heart Disease

Allopurinol, a drug commonly used to treat gout, provided no benefit in terms of reducing cardiovascular (CV) events in patients with ischemic heart disease, new randomized trial results show. Treatment of these patients without gout with 600 mg of allopurinol daily had no effect on composite primary endpoint outcomes, including nonfatal myocardial infarction (MI), nonfatal […]

Extreme risk protection orders assist in preventing mass shooting events, study shows

Extreme risk protection orders, also known as red flag laws, can help prevent firearm injury events, including multiple victim/mass shootings, by addressing the threat prior to an event occurring, according to new research led by the University of Michigan. A study by U-M’s Institute for Firearm Injury Prevention, in collaboration with the Johns Hopkins Bloomberg […]

Off-Hour Calls; Disabled Patients; and Birdsong for Anxiety

Legal Risks of Off-Hour Calls Physicians frequently receive off-hour calls, but failure to respond to them carries legal and other risks. Some 37% of respondents to Medscape’s Employed Physicians Report said that they deal with 1-5 hours of calls per month; 19% said that they have 6-10 hours of calls, and 12% reported 11 hours or […]

New Statement Guides the Diagnosis of Pediatric Anxiety

The Canadian Paediatric Society (CPS) has issued a position statement on the diagnosis of anxiety disorders in children and youth. The organization aims to “offer evidence-informed guidance to support pediatric health care providers making decisions around the care of children and adolescents with these conditions.” “It’s been a long time coming,” lead author Benjamin Klein, […]