Transcription factors are proteins that interact with DNA to regulate the function of some genes. Generally, a single transcription factor binds to several regions in the genome as it orchestrates complex cellular responses, which require the activation or inhibition of several genes. FoxH1 is an essential transcription factor during embryonic development, and, in adults, it […]
The debilitating effects of long-COVID in the U.S.
The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to the coronavirus disease 2019 (COVID-19) pandemic, which continues to cause immense social and economic disruptions worldwide. These effects are due to the high morbidity and mortality rates associated with COVID-19 and restrictions on human interactions due to public health interventions. In addition […]
Eczema and children: Emollients may help prevent the condition
Between 15% to 20% of children globally have eczema, also known as atopic dermatitis. There is currently no cure for eczema. Researchers from the Xinjiang Clinical Research Center for Dermatologic Diseases say that applying emollients to high-risk infants can help prevent eczema from forming. Between 15% to 20% of children around the world have eczema […]
‘All of us’: Big US genetics study is already helping participants
More than 155,000 people who have taken part in a massive genetic study orchestrated by the U.S. National Institutes of Health (NIH) have already gotten something in return—personalized DNA results that tell them whether they have an increased risk for certain health conditions. Called “All of Us,” the study aims to eventually include at least […]
States that restrict abortions have more maternal, infant deaths
In U.S. states with more restrictive abortion policies, rates of pregnant women, new mothers and infants dying were higher, a new report finds. The analysis, conducted by the Commonwealth Fund, found that states with heavily restricted access to abortion in 2020 had a maternal death rate that was 62% higher than states with easier abortion […]
Key to new lupus treatment could depend on protein in the blood
A new study has shown that restoring the balance of a protein in blood may be a promising treatment option for systemic lupus erythematosus, or lupus, an incurable autoimmune disease. The protein, CXCL5, helps to regulate the immune system through neutrophils, a type of white blood cell. In patients with lupus, the immune system which […]
Scientists identify multiple cell types that may contribute to treatment resistance in prostate cancer
Researchers have characterised prostate cancer cell dynamics at a single-cell resolution across the timespan of the disease — from its beginning to the point of androgen independence, where the tumour no longer responds to hormone deprivation therapy. Their study in mice, published today in eLife, reveals an expansion of intermediate cells that occurs in prostate […]
Pfizer Says It Is Working to Improve Supply of COVID Drug Paxlovid in China
(Reuters) – Drugmaker Pfizer Inc said on Tuesday it is working to improve supply of its COVID-19 antiviral drug Paxlovid in China in order to ensure adequate access to the drug as cases rise in the country. “Pfizer is actively collaborating with all stakeholders to secure an adequate supply of Paxlovid in China and remains […]
Kate Hudson Turned to This Mega-A-List Actor for Advice When Son Ryder Wanted to Go Skydiving
When Kate Hudson‘s eldest son, Ryder, revealed he wants to jump out of a plane for fun, she did what any other resourceful celebrity mom would do: Ask Mission Impossible alum and skydiving enthusiast Tom Cruise for advice. During a conversation with Glen Powell for Variety‘s “Actors on Actors” series, Hudson explained, “My son recently […]
Researcher shows connection between digital divide and COVID-19 outcomes
Two years into the pandemic, U.S. counties with lower home internet or computer access levels were seeing higher COVID-19 case and death rates, according to research by Fei Li, an assistant professor of urban studies at Georgia State University. “There’s a substantial gap between those who can and those who cannot benefit from information and […]