Madrigal Leads Race for NASH Treatments After Trial Success

(Reuters) – Madrigal Pharmaceuticals’ experimental drug met the main goals in a eagerly anticipated late-stage study, propelling it to the forefront in the race for the first approved treatment for patients with advanced liver scarring. Shares of the drugmaker surged more than three-fold on Monday after the positive data on resmetirom — a potential treatment for […]

Withdrawal of COVID-19 mitigation measures resulted in a rebound in Streptococcus pneumoniae cases in Germany

In a recent study posted to the medRxiv* preprint server, researchers from Germany conducted a population-based surveillance study to ascertain the etiology of community-acquired pneumonia (CAP) during the re-emergence of viral and bacterial respiratory diseases after the relaxation of coronavirus disease 2019 (COVID-19) containment and mitigation measures. Study: Streptococcus pneumoniae re-emerges as a cause of […]

Article on Sexual Orientation and Psychiatric Disorders Retracted

A paper about the potential influence of neurotransmitters on the development of sexual orientation and psychiatric disorders that caught flack on social media a year ago has now been retracted – so recently that the corresponding author said he didn’t know about the retraction until we asked him about it.  Late last year, Neuroscience & Biobehavioral […]

Best cooking fats for healthy cholesterol levels

Are you trying to remember which fat is the good fat to use in the kitchen? If you are confused about whether to use unsaturated fats, polyunsaturated, monounsaturated or saturated fats when cooking, it’s understandable. It can be confusing. Dr. Regis Fernandes, a Mayo Clinic cardiologist, says fats that raise your bad cholesterol levels and […]

Chinese pharma firm's COVID medicine awaits approval for entering market – local govt

BEIJING (Reuters) – Anhui Biochem Pharmaceutical’s self-developed COVID-19 treatment medicine has passed the clinical trial stages and professional reviews, and is waiting for regulatory approval to enter the market, said a statement released by China’s eastern Hefei government in Anhui province on Tuesday. The drug is targeted at adult patients with mild to moderate COVID […]

Radium-223 May Add Small Benefit in Bone-Metastatic Breast Cancer

The study covered in this summary was published on researchsquare.com as a preprint and has not yet been peer reviewed. Key Takeaway In patients with HR-positive bone-metastatic breast cancer, a pooled analysis of two trials showed a trend favoring radium-223 plus endocrine therapy compared with endocrine therapy alone for bone-related endpoints but not for progression-free […]

How to talk about your mental health with friends and family this Christmas

Written by Lauren Geall As Stylist’s digital writer, Lauren Geall writes on topics including mental health, wellbeing and women’s issues. She’s also a big fan of houseplants and likes to dabble in film and TV from time-to-time. You can find her on Twitter at @laurenjanegeall. Talking about your mental health can be an extremely difficult […]

MGI’s DNBSEQ-T7* facilitates ultra-deep sequencing of high-complexity metagenomic samples

Thanks to high-throughput sequencing technologies, shotgun metagenomic methods were made possible and had effectively transformed microbiology. Today, advances in both short- and long-read technologies are overcoming many of the previous challenges affecting metagenomic profiling, especially of highly complex samples and environment. Researchers from France's National Research Institute for Agriculture, Food, and Environment (INRAE) examined the […]

Lonely older heart failure patients more likely to suffer poor clinical outcomes

Older heart failure patients who feel that they have lost their social role amongst friends and family are more likely to suffer poor clinical outcomes. This is the finding of a new study in Frontiers in Cardiovascular Medicine that has examined the specific aspects of social interaction that can lead to a poor prognosis for […]

The COVID-19 pandemic's traumatizing effect on mothers in the USA

With the onset of the coronavirus disease 2019 (COVID-19) pandemic, family behaviors underwent a rapid forced change as work-from-home became the new norm due to social distancing recommendations. As the primary caregiver for children in most families, mothers typically shoulder the bulk of the increased responsibility at home as children must be educated, amused, and […]