Why do my legs feel like I’m wearing lead boots? DR MARTIN SCURR answers your health questions Both my legs are stiff and hot all the time, and from just under my knees I feel like I’m wearing lead boots. The hospital says it’s probably arthritis. Can you offer any further suggestions? I can’t go […]
Heartbreak of parents who still don’t know how their child died
We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Hannah Johnston should be looking forward to her youngest son William’s third birthday. But instead […]
Minor consent laws for STI/HIV services increased across US, but limitations persist
As of 2021, all 50 states and Washington, DC allow youth to consent independently to some or all of these services, but the laws remain complex and varied, and confidentiality protections are rare. Increasing sexually transmitted infection (STI) and HIV testing, treatment, and preventive services use among adolescents is key to decreasing STI and HIV […]
Stressed grad students tend to reach out to those who are similarly overwhelmed, shows longitudinal study
Stress is ubiquitous in today’s world and affects people’s lives significantly. Past research has focused on how stress is transmitted between pairs of individuals and in small groups. In a new longitudinal study, researchers adopted a network perspective to examine how the distribution of stress in an individuals’ social environment influences their appraisal of stress. […]
Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms
Identifying recurrent genetic alterations in myeloid neoplasms has improved diagnosis and expanded targeted treatments available to patients. However, treatment initiation can be delayed by the variable and lengthy turnaround times involved in testing for these alterations. In a novel study, researchers evaluated an integrated next-generation sequencing (NGS) system and found that it can deliver accurate, […]
Early diagnosis and treatment of Alzheimer’s disease by targeting toxic soluble Aβ oligomers
More than 55 million people worldwide were living with Alzheimer’s disease in 2020, according to Alzheimer’s Disease International. This figure is expected to almost double every 20 years, reaching 78 million in 2030 and 139 million in 2050. In 2021 the WHO Global Status Report estimated the annual worldwide cost of dementia as over $1.3 […]
AAHI awarded a $9.9 million project to develop prototype intranasal bivalent influenza RNA vaccine candidate
The Access to Advanced Health Institute (AAHI) announced today that it has been awarded a project agreement worth up to $9.9 million through the Medical CBRN Defense Consortium (MCDC) Other Transaction Authority (OTA) to develop a prototype intranasal bivalent influenza RNA vaccine candidate based on AAHI's self-amplifying RNA (saRNA) platform that targets both pandemic A(H5N1) […]
Gender norms linked to long-term pain may result in medically unjustified treatment disparities
Sensitive women and stoical men are the prevalent images of people in chronic pain. Unwarranted differences in medical treatment may result, as a University of Gothenburg doctoral thesis emphasizes. Approximately a fifth of the Swedish population have long-term pain that can affect their quality of life, work capacity, relationships, family life, and leisure activities. Treatment […]
‘Exciting’: Off-the-Shelf T-cell Therapy Shows Promise
Posoleucel, an investigational off-the-shelf T-cell therapy, showed promising safety and efficacy for eradicating multiple viruses in a phase 2 study of patients who previously underwent allogeneic stem cell transplant (allo-SCT). Of 58 adult and pediatric patients with a total of 70 viral infections at the time of enrollment in the open-label trial, 55 (95%) had […]
New type of immunotherapy effective in mice with ovarian cancer
CAR T-cell therapy, a certain kind of cancer treatment in which the immune system's T cells are programmed to attack tumor cells, is effective in mice with ovarian cancer, according to a study published in The Journal for ImmunoTherapy of Cancer. The researchers, who work at Karolinska Institutet, hope that the discovery will pave the […]