Why do I feel like I'm wearing lead boots? DR MARTIN SCURR answers

Why do my legs feel like I’m wearing lead boots? DR MARTIN SCURR answers your health questions Both my legs are stiff and hot all the time, and from just under my knees I feel like I’m wearing lead boots. The hospital says it’s probably arthritis. Can you offer any further suggestions? I can’t go […]

Heartbreak of parents who still don’t know how their child died

We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Hannah Johnston should be looking forward to her youngest son William’s third birthday. But instead […]

Minor consent laws for STI/HIV services increased across US, but limitations persist

As of 2021, all 50 states and Washington, DC allow youth to consent independently to some or all of these services, but the laws remain complex and varied, and confidentiality protections are rare. Increasing sexually transmitted infection (STI) and HIV testing, treatment, and preventive services use among adolescents is key to decreasing STI and HIV […]

Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

Identifying recurrent genetic alterations in myeloid neoplasms has improved diagnosis and expanded targeted treatments available to patients. However, treatment initiation can be delayed by the variable and lengthy turnaround times involved in testing for these alterations. In a novel study, researchers evaluated an integrated next-generation sequencing (NGS) system and found that it can deliver accurate, […]

Gender norms linked to long-term pain may result in medically unjustified treatment disparities

Sensitive women and stoical men are the prevalent images of people in chronic pain. Unwarranted differences in medical treatment may result, as a University of Gothenburg doctoral thesis emphasizes. Approximately a fifth of the Swedish population have long-term pain that can affect their quality of life, work capacity, relationships, family life, and leisure activities. Treatment […]

‘Exciting’: Off-the-Shelf T-cell Therapy Shows Promise

Posoleucel, an investigational off-the-shelf T-cell therapy, showed promising safety and efficacy for eradicating multiple viruses in a phase 2 study of patients who previously underwent allogeneic stem cell transplant (allo-SCT). Of 58 adult and pediatric patients with a total of 70 viral infections at the time of enrollment in the open-label trial, 55 (95%) had […]

New type of immunotherapy effective in mice with ovarian cancer

CAR T-cell therapy, a certain kind of cancer treatment in which the immune system's T cells are programmed to attack tumor cells, is effective in mice with ovarian cancer, according to a study published in The Journal for ImmunoTherapy of Cancer. The researchers, who work at Karolinska Institutet, hope that the discovery will pave the […]