Study: Pembrolizumab + chemo, trastuzumab beneficial in gastroesophageal cancer

For patients with HER2-positive gastroesophageal junction (GEJ) adenocarcinoma, pembrolizumab improves progression-free survival when combined with chemotherapy and trastuzumab, according to a study published online Oct. 20 in The Lancet. The research was published to coincide with the annual meeting of the European Society for Medical Oncology, held from Oct. 20 to 24 in Madrid. Yelena […]

How does oxidative stress during pregnancy influence the child’s behavior and emotional states?

A recent Molecular Psychiatry study investigates the association between maternal oxidative stress during pregnancy and early childhood mental disorders. Study: Maternal oxidative stress during pregnancy associated with emotional and behavioural problems in early childhood: Implications for foetal programming. Image Credit: Ground Picture / Shutterstock.com Background Many children develop mental disorders concomitant with emotional and behavioral problems […]

AI tool can detect distress in overburdened hospital workers

Artificial intelligence could aid in early detection of psychological distress among hospital workers, according to research conducted by New York University’s Grossman School of Medicine. WHY IT MATTERS The study, led by researchers at NYU Langone Health, demonstrates how AI was able to detect signs of mental stress among healthcare professionals. The research could hold […]

Why tuberculosis bacteria form long chains

A researcher team from Ecole Polytechnique Federal de Lausanne led by Dr. Vivek Thacker now group leader at the Department of Infectious Diseases at Heidelberg University Hospital have studied why tuberculosis bacteria form long strands and how this affects their infectivity. Their findings could lead to new therapies and have been published in the journal […]

Modifying the gut microbiota can ameliorate hypertensive kidney damage and inflammation

Reviewed New research in rodents indicates that altering gut microbes may affect the development of organ damage associated with hypertension. The findings will be presented at ASN Kidney Week 2023 November 1–November 5. For the study, scientists used narrow-spectrum antibiotics to specifically deplete Gram-negative or Gram-positive bacteria in rats with hypertension. Hypertension-related kidney damage and […]

New wearable ECG device could help prevent heart attacks

Reviewed A new compact, lightweight, gel-free and waterproof electrocardiogram (ECG) sensor offers more comfort and less skin irritation, compared to similar heart monitoring devices on the market. ECGs help manage cardiovascular disease – which affects around 4 million Australians and kills more than 100 people every day – by alerting users to seek medical care. […]

Expanding malaria treatment could help accelerate elimination

A clinical trial by Menzies School of Health Research (Menzies) published in The Lancet has revealed promising results to reduce malaria relapses, through the broader use of primaquine. Primaquine is a medication used for more than 60 years to target vivax malaria parasites in the liver and prevents infection from continuing. Usually only patients who […]

Lung cancer screening guidelines perpetuate racial disparities, study finds

Current national guidelines that rely on age and smoking exposure to recommend people for lung cancer screening are disproportionally failing minority populations including African Americans, according to a new study led by researchers at Stanford Medicine. An alternative risk-based method that incorporates additional information including family history and other health problems such as previous cancer […]

Genomic insights for prenatal screening: The advantages of low-pass genome sequencing

The importance of accurate prenatal diagnosis in preventing birth abnormalities cannot be overstated. Traditional karyotyping (a test to examine chromosomes in a sample of cells) dates back to the late 1960s and is well-established, but advancements in technology offer new options. A new study led by Dr. Sun Yan, Dr. Lijie Song, Dr. Xueqin Guo […]