Researchers describe incentivized programs to aid gene therapy developers

Providing an overview of the submissions process and examples of U.S. Food and Drug Administration (FDA) applications for Orphan Drug Designation (ODD) and Rare Pediatric Disease Designation (RPDD), a new article can help developers of gene therapies for rare genetic diseases. The article is published in the journal Human Gene Therapy. Anne Pariser and Elizabeth […]

In vitro 3D-engineered heart tissue that monitors drug-induced cardiotoxicity

Cardiotoxicity is a clinical condition that arises from using pharmaceutical agents such as antibiotics, which result in harmful effects on the heart, ultimately compromising its functional capacity. The left ventricle’s contractile ability is impaired, potentially leading to heart failure, a severe clinical outcome. Recently, a joint team of researchers from POSTECH and Georgia Institute of […]

Transplant from deceased donor with brain tumor appears to be safe

The risk for cancer transmission in transplants from deceased donors with primary brain tumors is low and long-term transplant outcomes are favorable, according to a study published online March 22 in JAMA Surgery. George H.B. Greenhall, M.B.Ch.B., from NHS Blood and Transplant in Bristol, England, and colleagues examined the risk for cancer transmission associated with […]

Expert highlights 11 early signs of dementia to spot in family

Dr Julia Jones discusses lifestyle changes to help prevent dementia We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Professor Matthew Cohen is the […]

Experts say there's little evidence exercise can stave off dementia

Why you CANT jog your memory: Experts say there’s no real evidence that regular exercise can stave off dementia Analysis showed ‘robust evidence’ is lacking to support claim it benefits brain READ MORE: The exercises that reveal how well you will age It may be good for your body. But there is little evidence regular […]

Research may speed identification of patients who need liver transplants

Research findings from Rutgers, the University of Michigan, the University of Texas Southwestern, and the Medical University of South Carolina could save lives by enabling faster and more accurate identification of hospitalized patients who need liver transplants or are likely to recover. Retrospective analysis of blood samples and medical records from 270 patients admitted to […]

I'm a dentist – here's how you're brushing your teeth all wrong

I’m a dentist – here’s how you’re brushing your teeth all wrong It is a myth that you should brush your teeth after you have eaten breakfast  Dr Alan Clarke and Dr Sam Jethwa revealed why you should brush before brekkie READ MORE: 11m Brits were unable to get an NHS dentist appointment last year  It’s a much followed […]

Mental illness makes you age QUICKER, according to scientists

Mental illness can age you QUICKER: Scientists find bipolar sufferers have bodies two years older than they actually are Researchers from King’s College London analysed data from 110,780 people  They looked for 168 different blood markers as well as their mental health history The scientists found those suffering with mental illness have accelerated ageing Read […]