Targeting part of an antiviral pathway triggered by the accumulation of a key pathogen shared in Alzheimer’s disease and frontotemporal dementia may one day offer a new therapeutic approach to deterring or delaying cognitive decline, according to preclinical research led by Weill Cornell Medicine scientists. The study, published April 24 in Nature Neuroscience, demonstrates that […]
Severe respiratory syncytial virus (RSV) infection has long been associated with the onset of childhood wheezing diseases, but the relationship between RSV infection during infancy and the development of childhood asthma has remained unclear. A new observational study by Vanderbilt University Medical Center researchers has found that RSV infection in the first year of life […]
In a new study, Harvard researchers took a granular approach to measuring the duration and frequency of suicidal thinking. With the help of a smartphone app, they were able to monitor participants multiple times a day over several weeks. These assessments revealed that suicidal thinking changes rapidly—with far shorter timescales than previously thought. And they […]
Dr. Ahmed Siddiqi, an orthopedic surgeon at Orthopaedic Institute Brielle Orthopaedics in New Jersey, started implementing models of digital, remote and hybrid care in early 2020. THE PROBLEM While the pandemic was one impetus, as an orthopedic surgeon, he also was eager to improve engagement and monitoring for his patients once they were discharged to […]
Seasonal variation in one of the hormones used to monitor thyroid function could in turn lead to false diagnoses of subclinical hypothyroidism and unnecessary prescriptions of levothyroxine, says Yale clinical chemist Joe M. El-Khoury, PhD. He says a Japanese study in more than 7000 healthy individuals showed that thyrotropin-stimulating hormone (TSH) varies widely throughout the […]
In a recent study published in Preventive Medicine Reports Journal, researchers performed a randomized clinical trial (RCT) to investigate whether adhering to the Mediterranean diet (MedDiet) with or without limiting calorie intake could improve cognition. Study: Effect of Mediterranean diet and Mediterranean diet plus calorie restriction on cognition, lifestyle, and cardiometabolic health: A randomized clinical trial. […]
Alcohol consumption increased substantially across the United States during the COVID-19 pandemic, but the impact was greatest among American Indian and Alaska Native (AIAN) populations, where deaths from alcohol-associated liver disease were six times those of white people, according to a study by Massachusetts General Hospital (MGH), a founding member of Mass General Brigham (MGB). […]
Problems with a sense of smell may predict a higher risk for age-related health problems, according to researchers from the Department of Otolaryngology–Head and Neck Surgery, Johns Hopkins University School of Medicine. What to Know Smell dysfunction acts as an early indicator of cognitive decline as well as signs of frailty in the brain and […]
Degeneration of myelin, an insulating sheath required for rapid communication between nerve cells, and neuroinflammation are notable hallmarks of Multiple Sclerosis (MS) and related neurodegenerative disorders such as Alzheimer's disease or Huntington's disease that affect roughly 2.8 million people in the world. However, little is known about the precise molecular steps by which demyelination leads […]
Experts recommend that women at least consider starting breast cancer screening once they turn 40. Now a new study suggests that is especially critical for Black women. Looking at data on U.S. breast cancer deaths, researchers found—as other studies have—that Black women in their 40s were substantially more likely to die of the disease than […]
