VIENNA — Naltrexone can be safely administered to patients with alcohol use disorder (AUD) and compensated cirrhosis to help them achieve abstinence and decrease craving, results of the first such randomized controlled trial (RCT) show. After 3 months, 64% of patients who received naltrexone were abstinent from alcohol , compared with 22% of patients who […]
Researchers from GeneDx have published a paper titled “Multiscale analysis of pangenomes enables improved representation of genomic diversity for repetitive and clinically relevant genes” in Nature Methods. The work details research in which the researchers developed a new computational tool, the PanGenome Research-Tool Kit (PGR-TK), for scalable analysis of clinically relevant genes that were previously […]
Findings Scientists at the UCLA Jonsson Comprehensive Cancer Center have identified potential new biomarkers that could indicate how someone diagnosed with metastatic melanoma will respond to immunotherapy treatment. The researchers found when T cells are activated, they release a protein called CXCL13, which helps attract more B cells and T cells to the tumor site. […]
Floods, bushfires, heat waves, cyclones. Australia is no stranger to emergencies. But during disasters we’re better prepared to support pet owners than families with babies and toddlers. Until now, the experiences and needs of families with very young children during emergencies have been largely invisible and overlooked. Our new research, a collaboration between the Australian […]
A former state medical board administrator alleges that making a whistleblower complaint against her previous hospital employer caused her to be fired from the state agency, according to a civil rights lawsuit filed June 2 in Maine’s superior court. The state, its medical board, and the board’s executive director are named as defendants. Brenda Gowesky, […]
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Scientists led by Sabine Taschner-Mandl, Ph.D., St. Anna Children’s Cancer Research Institute, and Nikolaus Fortelny, Ph.D., Paris Lodron University of Salzburg, are the first to analyze bone marrow metastases from childhood tumors of the nervous system using modern single-cell sequencing analysis. It turns out that cancer cells prevent cells in their environment from fighting the […]
A new study by Uppsala University shows that a higher body mass index (BMI) increases the risk of five different rheumatic diseases: rheumatism, osteoarthritis, gout, psoriatic arthritis and inflammatory spondylitis. The researchers also noted that BMI was a stronger risk factor for women compared to men in terms of gout and psoriatic arthritis. The study […]
When Emma Bishop got a persistent cough, she was told it was a chest infection that would go away on its own. But shockingly, the mum-of-two was later diagnosed with lung cancer, despite being a non-smoker and having no history of the disease in her family. The 38-year-old, who ran the London Marathon earlier this […]
